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The clinical and nonclinical safety record was subsequently marshaled in support of a Generally Recognized as Safe (GRAS) determination for AOD9604 as a dietary ingredient, conditional on publication of the underlying safety data [7]

GLP-1RAs were found to prevent progression of DR, 31 showed anti-inflammatory properties in the retina of diabetic mice, 32,33 and enhanced the vascular architecture of the retina

They are told to still go ahead with dose 2

& Azziz, R